the Stem Cell Source: cord blood and beyond

Here you'll find unique perspectives, commentary and information about a unique source of stem cells. As the global leader in the collection and preservation of newborn stem cells, Cord Blood Registry ® is playing a crucial role in advancing medical research using a child's own cord blood to treat conditions that have no cure today. Stay connected, spread the word, and learn more at our Web Site, www.cordblood.com.
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Cord Blood Stem Cells Save Lives

Posted: Apr 05, 2012

DISCLAIMER:
Banking newborn stem cells does not guarantee that the cells will provide a cure or be applicable for
every situation. Use will be determined by the treating physician who will consider if the stem cells are
applicable for the condition and whether they should come from the patient or a suitable donor. There
is no guarantee that an adequate stem cell match will be found for any given patient. Use of cord
blood and cord tissue in regenerative medicine is experimental. There is no guarantee that treatments
being studied in the laboratory or in clinical trials will be available in the future.

SOURCES:
1) http://www.babycenter.com/0_surprising-facts-about-birth-in-the-united-states_1372273.bc

2) This information was gained by adding together figures from childhood incidence of diseases and
extrapolation based on the 18-year figure (multiplying some annual figures by 18 to reach the
number).

3,500 children will get leukemia this year (almost all of them are acute leukemia). That figure
multiplied by 18 is 63,000.
http://www.cancer.org/cancer/cancerbasics/cancer-prevalence

353,000 children currently have cancer; one-third are estimated to be acute leukemia. That's 116,000.
http://www.cancer.org/cancer/cancerbasics/cancer-prevalence
http://www.cancer.gov/cancertopics/factsheet/Sites-Types/childhood

In the next 18 years, 3,900 people will have gotten aplastic anemia, based on the incidence of the
disease in the population and the number of children in the country.
http://marrow.org/Patient/Disease_and_Treatment/About_Your_Disease/Aplastic_Anemia/Aplastic_
Anemia_%28Severe%29.aspx

There are about 35 new cases of Diamond-Blackfan anemia in the U.S. and Canada each year; the
disease is normally diagnosed in infancy; that's more than 600 in the next 18 years
http://www.dbafoundation.org/faqs.php

20 kids are born with Fanconi anemia each year. In the next 18 years that is 360.
http://www.cincinnatichildrens.org/health/f/fanconi-anemia

Sickle cell disease affects 1 out of every 500 African-American newborns and 1 of every 1,000
Hispanic newborns. Using Census data on births and multiplying by 18, we arrive at 21,945 and 17,991.
http://www.cdc.gov/features/sicklecell
http://www.statehealthfacts.org/comparemaptable.jsp?ind=36&cat=2

As many as 20 patients with chronic granulomatous disease are born each year. Times 18, that's 360.
http://emedicine.medscape.com/article/956936-overview#a0199

In newborns and very young infants, Langerhans cell histiocytosis occurs in 2 per million; 4 million infants
born each year; times 18, that's 144.
https://www.histio.org/page.aspx?pid=379

As many as 100 kids are diagnosed with SCID each year. Times 18, that's 1,800.
http://www.genome.gov/13014325

Wiskott-Aldrich syndrome incidence is as much as 10 per million males. In the U.S., using newborn
figures, that's 367 in the next 18 years.
http://ghr.nlm.nih.gov/condition/wiskott-aldrich-syndrome
http://www.census.gov/compendia/statab/2012/tables/12s0080.pdf

Krabbe disease affects about 1 in 100,000 individuals. Using newborn figures, that's 738 in the
next 18 years.
http://ghr.nlm.nih.gov/condition/krabbe-disease
http://www.childstats.gov/americaschildren/tables/pop1.asp

Hurler's syndrome occurs in about one of every 100,000 babies born. Using the birth calculation, that's
738 in the next 18 years.
http://marrow.org/Patient/Disease_and_Treatment/About_Your_Disease/Metabolic_Disorders/Hurler_s_
Syndrome.aspx

Metachromatic leukodystrophy is reported to occur in 1 in 40,000 individuals. Using birth figures, that's
1,845 in the next 18 years.
http://ghr.nlm.nih.gov/condition/metachromatic-leukodystrophy

Sanfilippo syndrome is seen in about 1 in 70,000 births. That's 1,054 in the next 18 years.
http://www.nlm.nih.gov/medlineplus/ency/article/001210.htm

3) Nietfeld JJ, et al. Lifetime probabilities of hemapoietic stem cell transplantation in the U.S. Biol Blood
Marrow Transplant. Mar 2008;14(3):316-322

4) http://www.cancer.org/Cancer/CancerinChildren/DetailedGuide/cancer-in-children-types-of-childhood-c
ancers

5) http://www.cdc.gov/ncbddd/sicklecell/data.html

6) http://www.bidmc.org/YourHealth/ConditionsAZ.aspx?ChunkID=220846

7) http://019221f.netsolhost.com/carrierstats.shtml

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